Quick Answer: 200 mg/day CoQ10 is a practical starting point for fatigue. A 2022 meta-analysis found reduced fatigue with higher doses and longer duration; many feel changes within 1–2 weeks, with continued benefits by 4–8 weeks. Tsai 2022.

Who it helps

  • Men 40+ with afternoon slump; especially relevant if you’re on statins.

How it works

  • CoQ10 is central to mitochondrial electron transport; supplementation can improve fatigue outcomes. Tsai 2022.

How to use

  • Dose: 200 mg/day with a fat-containing meal.
  • Timing: Morning or lunch.
  • Duration: Reassess at 4 weeks.

What to avoid

Don’t expect stimulant-like effects; aim for consistency across weeks.

7‑day plan

  1. Take 200 mg daily.
  2. Track afternoon energy and steps.

CTA

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References

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